THERE is general agreement that the membrane process activates the contractile mechanism in muscle; but up to the present all efforts to find quantitative relations between the electrical and ...

The ability to modify the intracellular concentrations of divalent calcium ions is vital to normal cell functioning. In the cells of the cardiac muscle, calcium ions play a crucial role in coupling ...

I am interested in understanding the structures and fundamental mechanisms involved in cardiac excitation-contraction coupling, and how they change during development, ageing and heart disease. I am ...