Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

―NMR法によるDPPA3とUHRF1の複合体構造解析― 横浜市立大学大学院生命医科学研究科 構造生物学研究室 畑 圭一さん（2021年度博士前期課程修了）、有田 恭平教授、同研究科 構造エピゲノム研究室 小沼 剛助教、池上 貴久教授、理化学研究所 生命機能科学研究 ...

BOSTON, Aug. 26, 2025 (GLOBE NEWSWIRE) -- Life Biosciences (“Life Bio”), a biotechnology company pioneering cellular rejuvenation therapies to reverse and prevent multiple diseases of aging, today ...

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

These data, along with additional ER-100 preclinical data from a nonhuman primate model of NAION demonstrating clear restoration of methylation patterns with functional enrichment of neuronal ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...