Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

The diagram illustrates the SUMOylation pathway, including its key steps: maturation, activation, conjugation, ligation, and de-modification. The process begins with SUMO precursors undergoing ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...

These engineered cells produce a new amino acid that lights up the inner workings of enzymes, allowing researchers to observe biology unfold in real time. A recent Nature Communications study reports ...