Wet granulation, dry granulation and direct blending are the most popular granulation processes for solid dosage form manufacture in the pharmaceutical industry, but they each have distinct drawbacks.

Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Granulation processes are used for converting light fine powders into large, dense granules to make fast-dissolving drinks, optimized blends for compression tableting, and granules for waste water ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...