Download one of the releases, and pick the relevant proxy dll for your game. Place that dll in the same folder as the game executable. Place any plugin dlls you want to load in the Plugins folder.

With this plugin installed, you can start the game with SKSE64 and all its plugins loaded using the regular SkyrimSE.exe or SkyrimSELauncher.exe. This makes launching the game easier, as you no longer ...