Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying ...

The field of cancer research has increasingly focused on the metabolic underpinnings of tumorigenesis, recognizing how the reprogramming of cellular energy ...

Researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy found that an oral bacterium commonly associated with periodontal disease can promote ...

Why do some tumours spread while others remain localised? The mechanisms governing the metastatic potential of tumour cells remain largely unknown — yet understanding this is crucial for optimising ...

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening ...

Innovative use of stem cell technology to ramp up production of natural killer T cells could hold the key to improved cancer treatments. Cancer accounted for nearly 10 million deaths worldwide in 2020 ...

Cancer cells can brainwash their neighbors. Like the CIA deploying secret agents to turn an enemy, tumors use a similar strategy to manipulate nearby cells. The tumors’ agents are mitochondria, the ...

Although the respiratory system is one of the main entry points for microplastics and nanoplastics (MNPs) from the air into the body, little is known about the effects of these tiny particles on the ...

Circulating tumor cells were first described in 1869 by Thomas Ashworth, an Australian pathologist who observed them in a peripheral blood sample taken from a patient with metastatic cancer. 1 They ...

Genetic variation affects the expression of genes and function of proteins. DNA sequencing technologies have uncovered millions of genetic changes associated with various human traits and disease.