The tumor suppressor promyelocytic leukemia protein (PML) protein, first identified in a t(15;17) chromosomal translocation in patients with acute promyelocytic leukemia, 1 is the essential component ...
The promyelocytic leukemia protein (PML) is a tumor suppressor that is expressed at a low level in various cancers. Although post-translational modifications including SUMOylation, phosphorylation, ...
Oxidants and inflammatory mediators such as tumour necrosis factor-alpha (TNF-alpha) activate nuclear factor kappa B (NF-kappaB) and activator protein-1 (AP-1) transcription factors, and enhance the ...
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