Mitochondrial deoxyribonucleic acid (mtDNA) plays a crucial role in energy production and abnormalities in mtDNA are linked to various diseases. However, its regulatory mechanism remains ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Initiation of DNA synthesis: a general model from studies with prokaryotes -- Escherichia coli oriC -- Lambda phage origin: a familiar refrain -- Regulatory transcription factors and the initiation of ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...

The newly revealed structure of a key complex involved in copying DNA will lead to a better understanding of the process ...

Figure 1: An illustration showing RNA polymerase II (silver structure) transcribing DNA (yellow and orange helix) into messenger RNA. RIKEN researchers have conducted ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according ...