The accumulation of mutations in DNA is often mentioned as an explanation for the ageing process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in ...
A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...
To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...
To gain a deeper understanding of BKPyV replication and ways to prevent it, UAB researchers in the Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney ...
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