Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science ...

Dr. Tsubouchi concludes, "We propose that slow replication forks are not the manifestation of replication impediments but rather an integral feature of DNA replication in ES cells. Our study ...

理化学研究所（理研）生命機能科学研究センター発生エピジェネティクス研究チームの平谷伊智朗チームリーダー、高橋沙央里基礎科学特別研究員、三浦尚研究員、三重大学大学院医学系研究科の竹林慎一郎講師、柴田隆豊大学院生（研究当時）らの共同 ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library — your genome, which totals more than ...

The accumulation of mutations in DNA is often mentioned as an explanation for the ageing process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in ...