With the landmark discovery of the double-helical structure of DNA came the appreciation that the molecule’s two entwined strands are complementary — each serving as a template for the other during ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science ...

Humans and baker’s yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

King Abdullah University of Science & Technology (KAUST)Mar 19 2025 For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Mitochondrial deoxyribonucleic acid (mtDNA) plays a crucial role in energy production and abnormalities in mtDNA are linked to various diseases. However, its regulatory mechanism remains ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.