The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

理化学研究所（理研）生命機能科学研究センター発生エピジェネティクス研究チームの平谷伊智朗チームリーダー、高橋沙央里基礎科学特別研究員、三浦尚研究員、三重大学大学院医学系研究科の竹林慎一郎講師、柴田隆豊大学院生（研究当時）らの共同 ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Synthetic biology is poised to tackle a range of challenges, from cleaning up pollutants with designer bacteria to the creation of bespoke gene therapies. But the transition from the laboratory to ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...