The research group led by Professor Hitoshi Kurumizaka, Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, has revealed how the DNA repair ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA’s shape have an important influence on gene activity and energy production.

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...