Radiation Research, Vol. 131, No. 3 (Sep., 1992), pp. 309-314 (6 pages) The XR-V9B mutant of Chinese hamster V79 cells which exhibits hypersensitivity to ionizing radiation was isolated by the replica ...

Figure 1: FAAP250 is an integral component of the Fanconi anemia core complex. Figure 2: FAAP250 is required for FANCD2 monoubiquitination and is hyperphosphorylated in response to DNA damage. Figure ...

Figure 1: FANCB is a member of the core complex required for monoubiquitination of FANCD2. Figure 2: Nuclear localization of FAAP95 depends on FANCA. Figure 3: Evidence of a genetic defect in FAAP95 ...

Fanconi anemia (FA) is an autosomal recessive disorder characterized by diverse developmental abnormalities, progressive bone marrow failure, and a markedly increased incidence of malignancy. FA cells ...

The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy of cisplatin-based chemotherapy in non–small-cell lung cancer (NSCLC). Although ...

We retrospectively identified 163 patients with inoperable NSCLC and sufficient tumor tissue for ERCC1 analysis, who had received carboplatin and gemcitabine as first-line treatment.

Unresectable locally advanced cholangiocarcinoma treated with definitive radiation and gemcitabine. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include ...

Clin Cancer Res (2008) 14 (9): 2878–2886. Purpose: The excision repair cross-complementation group 1 (ERCC1) plays a pivotal role in DNA repair and has been linked to protection against carcinogenesis ...