The molybdenum cofactor (Moco) is an enzyme cofactor critical for the survival of almost all organisms from all kingdoms of life, and its biosynthesis is associated with various medical conditions ...

Oxygenases have long been thought to require a cofactor for catalysis. The structure of a vancomycin biosynthetic enzyme in complex with a substrate analog, and with molecular oxygen bound in its ...

This Research Topic is part of the Insights in Frontiers in Microbiology series launched in 2022. Cofactors such as NAD(P) +, NAD(P)H, FADH 2, and ATP are frequently seen to couple with microorganism ...

Nicotinamide adenine dinucleotide (phosphate) oxidases are the enzymes that catalyze the oxidation of NAD(P)H to produce NAD(P) +, which is the cofactor of many dehydrogenases. To reduce costs, ...

We present an artificial metalloenzyme based on the transcriptional regulator LmrR that exhibits dynamics involving the positioning of its abiological metal cofactor. The position of the cofactor, in ...

COFACTOR is a C++ program that computes the cofactor of a matrix, a fundamental operation in linear algebra. The cofactor of an element in a matrix is calculated by taking the determinant of the ...

ST. LOUIS--(BUSINESS WIRE)--Cofactor Genomics, Inc., a clinical-stage company bridging the precision medicine gap by decoding RNA, announced today the validation and launch of OncoPrism ®-NSCLC, an ...

Jarret Glasscock, founder and CEO, transitions to Chief Technology Officer (CTO), Board Member, and President ST. LOUIS, January 08, 2025--(BUSINESS WIRE)--Cofactor Genomics, Inc., a commercial-stage ...

Cofactor Genomics has announced an $18 million Series A financing round led by Menlo Ventures, with participation from DCVC, Ascension Ventures, iSelect, Y Combinator, Wilson Sonsini Goodrich & Rosati ...