Physically interacting proteins or parts of proteins are expected to evolve in a coordinated manner that preserves proper interactions. Such coevolution at the amino acid-sequence level is well ...

During the struggle for survival, populations occasionally evolve new functions that give them access to untapped ecological opportunities. Theory suggests that coevolution between species can promote ...

We study the problem of mapping proteins between two protein families in the presence of paralogs. This problem occurs as a difficult subproblem in coevolution-based computational approaches for ...

Protein function arises from a poorly understood pattern of energetic interactions between amino acid residues. Sequence-based strategies for deducing this pattern have been proposed, but lack of ...

Antagonistic coevolution between hosts and parasites, the reciprocal evolution of host resistance and parasite infectivity, has important implications in ecology and evolution. The dynamics of ...

In this course we have mainly discussed evolution within species, and evolution leading to speciation. Evolution by natural selection is caused by the interaction of populations/species with their ...

1 Biology Department, University of Massachusetts Boston, Boston, MA, United States 2 Biology Department, Syracuse University, Syracuse, NY, United States A long-standing problem in the study of ...