Synonymous codons are used non-randomly in the transcriptome to shape multiple aspects of translation. Optimal codons are associated with more efficient translation and correspond to cognate tRNA ...

Represented here by a tomato and a rope, ribosomes are central to all life on Earth because they help translate genetic information into proteins. Image by Gene-Wei Li/UCSF A hidden and never before ...

A hidden and never before recognized layer of information in the genetic code has been uncovered by a team of scientists, thanks to a new technique called ribosome profiling, which enables the ...