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The secret room a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
AZoLifeSciences on MSN

Deep learning–based codon optimization framework boosts protein expression in E coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...

Uncovering a secret room that a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
日本経済新聞

京大、ヒト細胞コドンの偏りがmRNAの安定性を制御しタンパク質発現 ...

ヒト細胞のコドン（遺伝暗号）に隠された暗号を解明 －ヒトコドン最適化制御による治療戦略の開発へ－ 竹内理 医学研究科教授らの研究グループは、ヒト細胞において、遺伝暗号であるコドンの偏りが、メッセンジャーRNA（mRNA）の安定性を制御し ...
Indian Defence Review

This Microbe Just Broke a Rule of Biology Scientists Thought Was Unbreakable

Scientists have identified a microbe capable of interpreting a single piece of genetic code in two completely different ways.

Unusual genetic code in Antarctic microbes yields rare amino acid

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...