AZoLifeSciences on MSN
DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gene therapy ...
A study conducted by researchers at Ohio State University and the New York University Grossman School of Medicine in the USA, has revealed that optimization of codon for bacterial expression causes ...
Two studies provide insights into the distinct strategies used by prokaryotes and eukaryotes to pause translation in order to facilitate cotranslational targeting of membrane proteins to the ...
中国検索エンジン市場でトップシェアをもつAIリーディングカンパニーである百度公司(本社:中国北京市、会長兼CEO:Robin Li)はLinearDesign と呼ばれる研究結果が世界トップクラスの学術誌「Nature」(シュプリンガーネイチャー・ジャパン株式会社)2023年5月号 ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
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