Although naturally occurring proteins form stable defined tertiary structures, it is well known that many proteins with non-natural sequences have unstructured conformations 1,2. This suggests that ...

Circular arrangement is one of the interesting topics of Permutations. Before understanding circular arrangement let us review some important concepts of linear permutation. In linear arrangement n ...

∥ Centre for High Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z1 ⊥ Department of Biochemistry and Molecular Biology, University of British Columbia, ...

Imagining that protein stability needs to be kept within some limits for biological function is easy. However, is there any corresponding pressure on protein folding and, hence, the dynamic ...

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, and Department of Biochemistry and Molecular Biology, State University of New ...

Circular permutations usually retain the native structure and function of a protein while inevitably perturbing its folding dynamics. By using simulations with a structure-based model and a rigorous ...

Abstract: We consider the problem of sorting a circular permutation by super short reversals (i.e., reversals of length at most 2), a problem that finds application in comparative genomics. Polynomial ...

//Hint 1: Use gray code to generate a n-bit sequence. //Hint 2: Rotate the sequence such that its first element is start. //Runtime: 176 ms, faster than 68.14% of C++ online submissions for Circular ...