Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Cell signaling pathways orchestrate essential cellular processes from growth to death. In cancer, these critical systems are hijacked, allowing malignant cells to evade control mechanisms and thrive.

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

A wave of recent neuroscience research has identified specific molecular and cellular mechanisms through which alcohol disrupts signaling between brain cells, offering a sharper picture of how ...

Pelvic organ prolapse (POP) represents a highly prevalent condition among women, particularly following childbirth and during aging, with recurrence rates following surgical intervention posing ...

Dedifferentiated liposarcoma lacks effective IGF-1→PPAR-γ adipogenic signaling due to epigenetic silencing of PPAR-γ2, with ...

Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...