For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest yeast ...

Scientists from The University of Manchester have changed our understanding of how cells in living organisms divide, which could revise what students are taught at school. In a Wellcome funded study ...

The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent ...

Image: High-resolution structure of the human protein complex SIN3B. Credit: Wan, Muhammad et al 2023. Researchers have revealed, at high-resolution, the structure of a human protein complex named ...

Our group investigates the molecular mechanisms of transcriptional regulation of the cyclin genes by the Muv-B complexes, during quiescence and mitosis initiation. The cell cycle is the fundamental ...