The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

The cell-cycle is an “engine” that regulates events in vivo. Much effort has been made to elucidate the mechanisms controlling this “engine”. However, it is difficult to monitor the dynamics of ...

Study: Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER. Image Credit: Anusorn Nakdee/Shutterstock.com In a recent study published in Nature ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

Summary image of the article. The upper part highlights neuronal cell cycle re-engagement is a stage proceeding neuronal senescence and that their full molecular profiles can now be identified by the ...

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this cell cycle re-entry and accumulation of resulting senescent neurons is more common in Alzheimer’s ...