JSTOR Daily

Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state

Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different ...
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AMO Pharma Limited: AMO Pharma Announces Preclinical Data Showing AMO-02 Improves Muscle Function, Glucose Handling and CNS function in Mouse Models of Duchenne Muscular D…

Findings from research collaboration with Brock University also show improved function in metabolic area and skeletal and cardiac muscle. LONDON, Sept. 19, 2023 /PRNewswire/ -- AMO Pharma Limited ...
EurekAlert!

A new therapeutic target for the prevention of heart failure due to aortic stenosis

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart Scientists at the ...
EurekAlert!

Blocking an ion channel improves muscle function and survival in mice with severe Duchenne muscular dystrophy

Johns Hopkins Medicine researchers discover that blocking the ion channel called TRPC6 in genetically modified mice with severe or moderate Duchenne muscular dystrophy (DMD) substantially improves ...