Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Genetic variation affects the expression of genes and function of proteins. DNA sequencing technologies have uncovered millions of genetic changes associated with various human traits and disease.

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...

Acute exercise triggers circulating changes that improve DNA damage repair and remodel gene expression in colon cancer cells, ...

A new review reveals how folic acid can act as both a friend and foe in breast cancer, protecting at moderate doses, but potentially fueling tumor growth when intake is excessive or genes go awry.