T cells, also known as T lymphocytes, are the immune cells that drive the cellular immune response. There are several different types of T cells, each playing a distinct role. The functions of T cells ...

This TCR was then isolated and artificially expressed in other CD4 T cells. We then evaluated the effectiveness of these engineered cells against cancer cells, both in vitro and in animal models. The ...

The brain and spinal cord were once thought to enjoy immune privilege, meaning they were believed to be largely insulated from immune activity elsewhere in the body. In recent years, however, ...

Scientists from the RIKEN Center for Integrative Medical Science (IMS) and Keio University School of Medicine in Japan have used single-cell RNA analysis to find that supercentenarians—meaning people ...

Researchers at Institute of Science Tokyo uncover the function of double negative T cells, an unconventional type of immune cells found in the intestine. These cells play an important role in ...

Scientists analyzing human and mouse pancreatic lymph nodes (PLNs) and spleens have identified a distinct subset of CD4 memory helper T cells associated with type 1 diabetes (T1D). Reported by ...

Immune cells called double negative T cells are abundant in the intestine but have been poorly understood till date. In a recent study, researchers from the Institute of Science Tokyo report that ...