New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...

This article and associated images are based on a poster originally authored by Sam Hoare, Luciana Leo, Anastasia Schultz, and Thom Hughes and presented at ELRIG Drug Discovery 2025 in affiliation ...

Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive. Because the molecules suppress breathing and heart function, those drugs can ...