Akira innate immunity group has been studying the roles of Toll-like receptors and signaling, mainly by generating the knockout mice and analyzing them. Up to now, eleven members of the TLR family ...

It was long believed that acquired immunity—a type of immunity mediated by T- and B-cells—had memory, meaning that it could learn from new pathogens, making subsequent reactions more effective, ...

The innate immune system serves as the body's first line of defence, rapidly detecting and responding to external pathogens and internal damage. Recent advances in the field have highlighted the ...

The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by the Radboudumc shows how this ...

Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Detailed immune profiling in long-term care populations reveals that SARS-CoV-2 vaccines and infections drive powerful virus-specific responses while leaving lifelong common cold immunity largely ...