Pro-opiomelanocortin (POMC)-expressing neurons in the hypothalamic arcuate nucleus (ARC) play key roles in feeding and energy homoeostasis, hence their development is of great research interest. As ...

The bone morphogenetic proteins (BMPs) are a group of potent morphogens which are critical for the patterning, development, and function of the central nervous system. The appropriate function of the ...

This comprehensive scRNAseq atlas of the cranial region during neural induction, patterning, and morphogenesis provides a fundamental demonstration of how different cell fates are organized in ...

In the vertebrate embryo, neural cell types are organized spatially along the dorsoventral axis of the neural tube and differ by expression of cell-intrinsic determinants and by their adhesive and ...

Summary: Researchers unveil the role of cytonemes, thin cell projections, in neural development. These hair-like structures facilitate direct signal transport across cells, impacting nervous system ...

Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee 37235, United States Center for Stem Cell Biology, Vanderbilt University, Nashville, Tennessee 37235, United ...

New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year -- most of the life span of a mouse -- and give rise to multiple types ...